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Reference:

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[] https://stemcellres.biomedcentral.com/articles/10.1186/s13287-023-03357-w

[] https://nationalzoo.si.edu/animals/american-alligator#:~:text=Alligators%20have%20between%2074%20and,are%20larger%20than%20female%20alligators.

[] https://expressdentist.com/dental-statistics/#:~:text=65%20million%20Americans%20have%20periodontitis,men%20and%2038%25%20are%20women.

[] https://www.usnews.com/news/articles/2013/05/13/alligators-can-grow-new-teeth-so-why-not-humans#:~:text=%22When%20the%20mature%20tooth%20falls,cell%20there%20under%20normal%20conditions.%22, https://www.kcl.ac.uk/news/natural-tooth-repair-method-discovered-by-kings-college-london-can-also-be-used-on-common-cavities-protecting-teeth-from-further-damage-2

[] https://www.scientificamerican.com/article/instead-of-filling-cavities-dentists-may-soon-regenerate-teeth1/

[] https://www.foxnews.com/health/filling-a-cavity-may-never-be-the-same, https://www.nbcnews.com/mach/science/next-revolution-dental-care-about-begin-ncna837706, https://www.vice.com/en/article/qkjm9v/an-alzheimers-drug-could-help-grow-teeth-and-fight-cavities

[] https://www.smithsonianmag.com/science-nature/solving-an-alligator-mystery-may-help-humans-regrow-lost-teeth-60257334/

[] https://www.kcl.ac.uk/news/natural-tooth-repair-method-discovered-by-kings-college-london-can-also-be-used-on-common-cavities-protecting-teeth-from-further-damage-2

[] https://www.sciencefocus.com/the-human-body/why-cant-we-regrow-teeth

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[] According to the study, “SAGE treatment significantly decreased…clinical attachment loss by about 23%...”. Clinical attachment loss refers to the loss of bone and gum tissue surrounding the tooth.

[] This study also found that “IL- 6 concentrations showed a statistically significant reduction of about 27%, 57% and 37% in SAGE treated group compared to control group in all 4, 8 and 12 week time period...” IL-6 is a marker for gingivitis. In short, this means after 8 weeks, sage decreased this gingivitis marker by 57%.

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